Elsevier MDL collaborates with NIH to catalog biological properties of small molecules

“Elsevier MDL is pleased to collaborate with the NIH to give commercial, academic and governmental researchers broader access to vital research information,” said Elsevier MDL CEO Lars Barfod. “xPharm provides its licensed customers an ideal set of compounds for medicinal chemists, biologists, pharmacologists and other researchers to determine starting points for pharmacological research. The addition of xPharm chemical structures makes PubChem an even more valuable resource, allowing researchers who have licensed xPharm to link from chemistry and biology data in PubChem to authoritative pharmacology data and associated target and disorder data.”

“We're pleased to have the support of Elsevier MDL, and welcome these biologically very interesting new links from the xPharm database in PubChem,” said Steve Bryant, Director, PubChem, National Institute of Health. “It is our intent to make PubChem as comprehensive as possible and this type of collaborative effort is invaluable.”

xPharm is a comprehensive and authoritative collection of pharmacological data, with chemical agents representing the best examples of pharmacological activity. The interlinked biological and pharmacological disorder data combines to provide researchers with more detailed pharmacology data in a single online source. xPharm is available via the online DiscoveryGate® platform for accessing integrated scientific content from databases, journal articles, patent publications and reference works. xPharm structures in PubChem will be linked directly to their corresponding pharmacological data on DiscoveryGate.

The contribution of xPharm structures marks the first step in Elsevier MDL’s efforts to support the NIH Roadmap initiative. Elsevier MDL and NIH plan additional collaboration related to the PubChem database in the future.

Read the press release